Chemical Reagents for Protein Modification, Fourth Edition by Roger L. Lundblad

By Roger L. Lundblad

The use of the chemical amendment of proteins has advanced over the last eighty years, taking advantage of advances in analytical, actual, and natural chemistry. over the last 30 years, using chemical reagents to switch proteins has been an important in making a choice on the functionality and constitution of purified proteins. This groundbreaking paintings is a part of the root of rising disciplines of proteomics, chemical biology, constitution biology, and chemical proteomics.

Chemical Reagents for Protein amendment, Fourth Edition presents a accomplished overview of reagents used for the chemical amendment of proteins, representing a massive revision of the paintings offered in earlier versions. The thoroughly up to date Fourth version is considerably higher and contains 5 new chapters:




  • Alkylating Agents

  • Acylating Agents

  • Nitration and Nitrosylation

  • Oxidation

  • Modification of Proteins with decreasing Agents


There is vastly elevated assurance of the chemical amendment of cysteine, that is serious for bioconjugate synthesis. The bankruptcy on relief additionally offers info valuable for bioconjugate synthesis in addition to for the processing of inclusion our bodies. The e-book areas emphasis on stipulations that have an effect on the specificity of the chemical amendment of proteins, akin to solvent and temperature. The structure has been markedly revised, providing info in accordance with the chemical nature of the editing fabric and at the amino acid residue changed. This re-creation has elevated importance to biopharmaceuticals. a lot of the data is in tabular shape, which allows the speedy situation of stated material.

Show description

Read or Download Chemical Reagents for Protein Modification, Fourth Edition PDF

Similar molecular biology books

Verlust der Selbst-Grenzen: Entwurf einer interdisziplinären Theorie der Schizophrenie (German Edition)

Die Entstehungsbedingungen der Schizophrenie, einer meist chronisch verlaufenden psychobiologischen Erkrankung, unter der mindestens 1% der Weltbevölkerung leidet, sind trotz intensiver Forschungen nach wie vor unbekannt. Die vorliegende Monographie legt ein Erklärungsmodell der Schizophrenie vor, wobei sich die molekulare Hypothese auf die Störung der Hirnfunktionen übertragen lässt und davon die schizophrenen Symptome sowie das Wirklichkeitserleben dieser Patienten abgeleitet werden kann.

Microbial Biochemistry

Microbial body structure, biochemistry, and genetics allowed the formula of recommendations that grew to become out to be vital within the learn of upper organisms. within the first part, the foundations of bacterial progress are given, in addition to the outline of the several layers that enclose the bacterial cytoplasm, and their function in acquiring nutrition from the surface media via assorted permeability mechanism defined intimately.

Interactive Probiotics

This publication underlines the significance of reciprocal interactions among probiotics and people when it comes to pressure induction, epigenetic keep an eye on of mobile responses, oxidative prestige, bioactive molecules biosynthesis, moonlighting proteins secretion, endogenous pollution neutralization, and a number of other organic features.

Single Cell Sequencing and Systems Immunology (Translational Bioinformatics)

The quantity specializes in the genomics, proteomics, metabolomics, and bioinformatics of a unmarried mobile, specifically lymphocytes and on knowing the molecular mechanisms of platforms immunology. in line with the author’s own event, it presents revealing insights into the capability purposes, value, workflow, comparability, destiny views and demanding situations of single-cell sequencing for making a choice on and constructing disease-specific biomarkers in an effort to comprehend the organic functionality, activation and disorder of unmarried cells and lymphocytes and to discover their practical roles and responses to treatments.

Extra info for Chemical Reagents for Protein Modification, Fourth Edition

Sample text

Download PDF sample

Rated 4.53 of 5 – based on 48 votes