ADAMTS13: Biology and Disease by George M. Rodgers
By George M. Rodgers
This accomplished quantity discusses the protease ADAMTS13, summarizing the present prestige of simple and medical study. The 9 authoritative chapters commence with a historic point of view by way of exploration of the biochemistry and structure-function relationships of ADAMTS13 in addition to its common functionality in hemostasis (cleavage of von Willebrand factor). rising examine subject matters for ADAMTS13 are lined, together with its power position in angiogenesis and different facets of phone biology. extra subject matters comprise laboratory assays for ADAMTS13, inherited ADAMTS13 deficiency, and purchased ADAMTS13 deficiency. A bankruptcy on similar thrombotic microangiopathic (TMA) problems examines the diversities among TMAs linked to ADAMTS13 deficiency and people now not linked to ADAMTS13 deficiency. a last bankruptcy experiences the initial info on rising facets of ADAMTS13, resembling the prestige of recombinant ADAMTS13 items and their power utility.
Comprehensive in its exploration of the ADAMTS13 protease in disease, ADAMTS13: Biology and disorder is an important source for scientific hematologists, transfusion drugs physicians, and researchers drawn to hemostasis, vascular biology, biochemistry, and metalloproteases.
Read or Download ADAMTS13: Biology and Disease PDF
Similar molecular biology books
Die Entstehungsbedingungen der Schizophrenie, einer meist chronisch verlaufenden psychobiologischen Erkrankung, unter der mindestens 1% der Weltbevölkerung leidet, sind trotz intensiver Forschungen nach wie vor unbekannt. Die vorliegende Monographie legt ein Erklärungsmodell der Schizophrenie vor, wobei sich die molekulare Hypothese auf die Störung der Hirnfunktionen übertragen lässt und davon die schizophrenen Symptome sowie das Wirklichkeitserleben dieser Patienten abgeleitet werden kann.
Microbial body structure, biochemistry, and genetics allowed the formula of innovations that grew to become out to be vital within the research of upper organisms. within the first part, the rules of bacterial progress are given, in addition to the outline of the several layers that enclose the bacterial cytoplasm, and their function in acquiring nutrition from the surface media via diverse permeability mechanism defined intimately.
This booklet underlines the significance of reciprocal interactions among probiotics and people by way of pressure induction, epigenetic keep an eye on of mobile responses, oxidative prestige, bioactive molecules biosynthesis, moonlighting proteins secretion, endogenous pollutants neutralization, and several organic services.
Single Cell Sequencing and Systems Immunology (Translational Bioinformatics)
The quantity specializes in the genomics, proteomics, metabolomics, and bioinformatics of a unmarried telephone, specially lymphocytes and on knowing the molecular mechanisms of structures immunology. in response to the author’s own adventure, it presents revealing insights into the aptitude purposes, value, workflow, comparability, destiny views and demanding situations of single-cell sequencing for making a choice on and constructing disease-specific biomarkers with the intention to comprehend the organic functionality, activation and disorder of unmarried cells and lymphocytes and to discover their sensible roles and responses to remedies.
Extra resources for ADAMTS13: Biology and Disease
Example text
