By George M. Rodgers
This accomplished quantity discusses the protease ADAMTS13, summarizing the present prestige of simple and medical study. The 9 authoritative chapters commence with a historic point of view by way of exploration of the biochemistry and structure-function relationships of ADAMTS13 in addition to its common functionality in hemostasis (cleavage of von Willebrand factor). rising examine subject matters for ADAMTS13 are lined, together with its power position in angiogenesis and different facets of phone biology. extra subject matters comprise laboratory assays for ADAMTS13, inherited ADAMTS13 deficiency, and purchased ADAMTS13 deficiency. A bankruptcy on similar thrombotic microangiopathic (TMA) problems examines the diversities among TMAs linked to ADAMTS13 deficiency and people now not linked to ADAMTS13 deficiency. a last bankruptcy experiences the initial info on rising facets of ADAMTS13, resembling the prestige of recombinant ADAMTS13 items and their power utility.
Comprehensive in its exploration of the ADAMTS13 protease in disease, ADAMTS13: Biology and disorder is an important source for scientific hematologists, transfusion drugs physicians, and researchers drawn to hemostasis, vascular biology, biochemistry, and metalloproteases.
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